Lipid droplets and their interactions with other organelles in liver diseases

Lipid droplets are cellular organelles used for lipid storage with a hydrophobic core of neutral lipids enclosed by phospholipid monolayer. Besides presenting as giant single in fat tissue, also widely present multitude small structures hepatocytes, where they play key roles health and disease the liver. In addition to storage, directly involved metabolism, membrane biosynthesis, cell signaling, inflammation, pathogen-host interaction cancer development. addition, interact other regulate biology. It is fair say that exact functions physiology remain largely obscure. Thus prompted, here we aim analyze corpus contemporary biomedical literature create framework how role hepatocyte pathophysiology should be understood. The resulting help understanding important liver diseases, including fatty disease, viral hepatitis direct further research directions.